Lived in the Clear Lake area for 11 years before moving to VA. I would not recommend it if you have to go to downtown. Mass transit was minimal when I lived there (mainly buses up 45), but if they have that, then it might be worth it. I would consider looking to the west...say Austin!!
(My first thought when I saw you were in Austin was
WHY???)
Not sure how familar you are with Houston, but remember the humidity is brutal and they get their fair share of tropical storms and hurricanes. Even a heavy summer afternoon rain shower is enough to flood streets and major roads...
The weather there was one of the big reasons I ended up moving out.